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 Echinacea Extract Introduction



Echinacea extract is one of the most widely used medicinal plants and is commonly used for colds, toothaches, snake bites and other injuries. The United States has used it as an alternative medicine for strengthening the immune system and clearing blood for many years, especially during the seasons of seasonal changes and cold coughing.

History

Echinacea is the most widely used medicinal plant in the Plains Indian tribe and is commonly used for colds, toothaches, snake bites and other injuries. Native Americans have used it as an alternative medicine to boost the immune system and clear blood for many years, especially during seasonal changes and the common season of cold and cough. In 1887, it was introduced into the US comprehensive treatment system and was promoted for use in a variety of diseases ranging from colds to syphilis. Modern research on the herb began in Germany in the 1930s.

Main Function

The main active ingredients of Echinacea, polyphenols, caffeic acid derivatives and polysaccharides have the following functions:

1.Immunostimulatory effect
Inulin: By increasing the number of granulocytes and leukocytes, it increases the chemotaxis of monocytes and neutral viruses and produces bacteriolysis.
Polysaccharides: T lymphocytes and hydrocarbon receptors on the surface of macrophages produce immunostimulatory effects, which can increase the phagocytic capacity of macrophages and stimulate macrophages to increase the number of tumor necrosis factor, interferon, and leukocyte mediators. Destroy tumor cells.
Alkylamines and caffeic acid derivatives: lipophilic alkylamines increase macrophage phagocytosis.
Echinacea: increase the activity of non-specific T cells, produce interferon, promote lymphocyte secretion, reduce T-helper cells, and reduce the ratio of T-helper cells to inhibitory factors.

2. Tissue renewal and anti-infection
Inhibition of hyaluronidase (hyaluronidase) can stimulate the growth of fibroblasts and the synthesis of glucosamine, produce corticosterone and promote the secretion of adrenocortical hormone. Polysaccharides have an anti-infective effect.

3. Antibacterial effect
Echinacea and caffeic acid derivatives have weak antibacterial activity.

4. Antiviral effect
It can inhibit influenza, herpes and foaming viruses. The antiviral activity is attributed to the inhibition of hyaluronidase and can block the viral receptors on the cell surface.

5. Toxic side reactions
Excessive dosage will lead to low fever, and dermatitis may occur in sensitive people. Scope of application:
Echinacea and its extracts for common infections or wounds, colds or flu, rosary virus, candiditis, staphylococcal infection, urinary tract infections, pelvic inflammation (PID), tonsil inflammation, upper respiratory tract infections, wound inflammation, toothache Or oral infections, mosquitoes, animal or snake bites, blood food poisoning, lice, abscesses, eczema, etc. Improve sore throat caused by acute and chronic pharyngitis, dry and hot, hoarseness; strengthen the immune system, prevent flu, shorten colds, reduce sore throat, mild infection, cold, cough, flu and other upper respiratory symptoms . Promoting protein synthesis and participating in both synthetic and immune-related enzymes play an important role. Run bone marrow and improve immunity. Effectively improve symptoms such as recurrent oral ulcers, respiratory tract infections and digestive tract infections.

Chemical Composition

Echinacea extract is mainly composed of chrysinic acid and its chemical structure is as follows:
Choric acid C22H18O12
Chinese name: cichoric acid
Chinese alias: 2R, 3R)-2,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]succinic acid
English name: Cichoric acid
English alias: (2R, 3R)-2,3-bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]butanedioic acid CAS No.: 70831-56-0
Molecular formula: C22H18O12
Molecular weight: 474.37

Pharmacological Action

Hypoglycemic, lipid-lowering, anti-allergic, anti-allergic, uric acid-lowering, cichoric acid can inhibit hyaluronidase and HIV-1 integrase, and has cell phagocytosis and antiviral activity in vitro and in vivo.
The polysaccharides and caffeic acid derivatives of polyphenols in this product can enhance the body immunity by increasing granulocyte and leukocytes and enhancing T cell activity and phagocytic ability of macrophages, inhibiting the growth of adrenal cortex hormones by inhibition of hyaluronidase. Influenza, herpes, and antibacterial and anti-infective effects. Can be used for a variety of diseases such as influenza, traumatic infections.

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